STABLE version -- 5.1.1130.129

[QZMTCH]

creates a bunch of empty chrome_url_fetcher folders in the Program Files folder

this is a problem with all chromiums. If you run the browser as an administrator or with an administrator account, the browser considers the temp folder dangerous and works in the program files folder. It should delete these folders after itself, but often does not.
https://issuetracker.google.com/issues/42323359
https://chromium-review.googlesource.com...b=comments

and here the user suggested to change this behavior in the code for supermium, and while the developer has not changed it, he suggested a patch dll. For other chromes you can probably also use such a patch, I have not tried
https://github.com/win32ss/supermium/issues/684
and in cent means that it is already fixed in the code